Her expertise in data engineering and large scale database generation has been helped in building research databases for the Healthcare Cost and Utilization Project (HCUP) and Social Determinants of Health (SDOH) for the Agency for Healthcare Research and Quality (AHRQ), as well as the Component 2 pay data collection for the Equal Employment Opportunity Commission (EEOC).

Bryn has been involved in the National Survey of Early Care and Education (NSECE) since 2019, where she developed the weights and public use and restricted use files. She continued this work for the COVID-19 follow-up surveys and is now working on the 2024 survey.

Prior to NORC, Bryn was a lead data engineer at a health care data analytics firm, and researched Medicare claims data for alternative bundled payment modeling, and the analysis of emergency department episodes and outcomes for the American College of Emergency Physicians.